Hydronephrosis birth defects may strike after a mother’s Paxil use

The birth defect known as hydronephrosis is a urinary tract defect in which the flow of urine from the body is obstructed, leading to dilation (enlargement or stretching) or a distension of the kidney with urine backed up from the bladder.

This sometimes causes kidney stones, among other related injuries. The hydronephrosis blockage also can lead to defects of the stomach, heart or spinal cord.

About one in 500 babies is born with this birth defect, and more are male then female.  

Most newborn infants suffering hydronephrosis will grow out of the condition within about the first two years of life and may not require treatment. But if the condition persists and kidney function is affected, surgery or other treatment may be needed to remove the obstruction.

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Undescended testes are among Paxil birth defects

Almost a third of premature infant boys and around 3% of full-term male births involve the condition of cryptorchidism, also known as undescended testes or testis. This means one or both testes are absent from the infant boy’s scrotum.

About four in every five boys suffering a case of cryptorchid testes have their testes or testis descend during their first year of life, if not the first few months. Others may need special care.

Around one third of these cases involves both testes, while the other two third involve only one testis.  The undescended testis or testes may be found in the inguinal canal, may be under the skin of the thigh, may be undeveloped, may have vanished or may be found in the abdomen near the kidney.

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Hypospadias urinary tract birth defect may owe to Paxil use in pregnancy

About one in every 250 male babies in America is born with a urinary tract birth defect known as hypospadias. A hypospadias urinary tract birth defect occurs when the opening of the urethra is found underneath the penis rather than on its tip. This can be determined easily via a physical examination at birth.

A hypospadias birth defect for a newborn infant or baby can vary in severity. Usually the urethra opening is found near the tip of the penis, or on the underside. But in some cases it is found in the middle or close to the base of the penis, or even behind or in the scrotum.

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